Preheat the oven to 350° In a huge mixing bowl combine the ground meat, chopped onions, egg, garlic powder, Italian seasoning, 1/2 cup of ketchup, bread crumbs plus salt and pepper. Use your hands to mix everything together.
Press the meat mixture in the loaf pan. Brush the top with the last 1/2 cup of ketchup.
Cover with foil then bake it in the oven for 45 minutes. Take it out of the oven after 45 minutes, take the foil out then brush the top with a little bit more of ketchup. Return to the oven to bake for another 15 minutes.
Transfer in a serving platter. Slice carefully.